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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INSRR All Species: 9.39
Human Site: T582 Identified Species: 22.96
UniProt: P14616 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P14616 NP_055030.1 1297 143720 T582 V R A I T L T T E E D S P H Q
Chimpanzee Pan troglodytes Q5IS37 825 92786 Q175 I R W M Q L W Q E Q G E A K L
Rhesus Macaque Macaca mulatta XP_001100407 1367 154946 M588 V K A V T L T M V E N D H I R
Dog Lupus familis XP_547526 1300 144046 T582 V R A I T L T T A E D S P H Q
Cat Felis silvestris
Mouse Mus musculus Q9WTL4 1300 144727 T582 V R A I T L T T A E D S P H Q
Rat Rattus norvegicus P24062 1370 155377 M589 V K A V T L T M V E N D H I R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P08941 2311 260942 S955 I P S S V P E S S F K I K G N
Frog Xenopus laevis O73798 1358 153845 M582 V K A I T L T M L E N R H I H
Zebra Danio Brachydanio rerio NP_694500 1405 158428 V585 V K A V T L V V E D K H V G G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P09208 2144 239757 M906 Y S Y Y V R T M A I S S E L T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 22.2 54.2 92.3 N.A. 88.8 54.2 N.A. N.A. 21.2 52.6 50.8 N.A. 26 N.A. N.A. N.A.
Protein Similarity: 100 37.1 69.1 95.4 N.A. 92.7 68.9 N.A. N.A. 33.4 67.6 65.1 N.A. 36.6 N.A. N.A. N.A.
P-Site Identity: 100 20 40 93.3 N.A. 93.3 40 N.A. N.A. 0 46.6 33.3 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 40 66.6 93.3 N.A. 93.3 66.6 N.A. N.A. 20 60 53.3 N.A. 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 70 0 0 0 0 0 30 0 0 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 10 30 20 0 0 0 % D
% Glu: 0 0 0 0 0 0 10 0 30 60 0 10 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 10 0 0 20 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 10 30 30 10 % H
% Ile: 20 0 0 40 0 0 0 0 0 10 0 10 0 30 0 % I
% Lys: 0 40 0 0 0 0 0 0 0 0 20 0 10 10 0 % K
% Leu: 0 0 0 0 0 80 0 0 10 0 0 0 0 10 10 % L
% Met: 0 0 0 10 0 0 0 40 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 30 0 0 0 10 % N
% Pro: 0 10 0 0 0 10 0 0 0 0 0 0 30 0 0 % P
% Gln: 0 0 0 0 10 0 0 10 0 10 0 0 0 0 30 % Q
% Arg: 0 40 0 0 0 10 0 0 0 0 0 10 0 0 20 % R
% Ser: 0 10 10 10 0 0 0 10 10 0 10 40 0 0 0 % S
% Thr: 0 0 0 0 70 0 70 30 0 0 0 0 0 0 10 % T
% Val: 70 0 0 30 20 0 10 10 20 0 0 0 10 0 0 % V
% Trp: 0 0 10 0 0 0 10 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 10 10 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _